Resultados de Búsqueda
Parálisis del nervio facial: Complicación inusual en pacientes con mucormicosis post COVID-19. Facial nerve palsy: Unusual complication in patients with post COVID-19 mucormycosis
SummaryLeer artículo completo
Disección de las fibras de sustancia blanca cerebral usando el método de Klinger en neurociencias. Dissection of cerebral white matter fibers using the Klinger method in neuroscience
SummaryLeer artículo completo
White matter hyperintensities severity and progression are not related to earlobe crease presence. A cross-sectional and longitudinal prospective study in community-dwelling older adults. La severidad y progresión de hiperintensidades de la sustancia blanca no están relacionados con la presencia del pliegue del lóbulo de la oreja. Un estudio transversal y longitudinal prospectivo en una población de adultos mayores
SummaryBackground: Earlobe crease (ELC) has been associated with coronary atherosclerosis. Recently, ELC has been associated with white matter hyperintensities (WMH) of presumed vascular origin. However, the results are heterogeneous among studies. We aimed to assess whether ELC is associated with WMH severity and progression in community-dwelling older adults.
Methods: Atahualpa Project Cohort participants received earlobe photographs and brain MRIs to assess the association between ELC and WMH severity, as well as the relationship between ELC and WMH progression using ordinal logistic and Poisson regression models, respectively.
Results: The cross-sectional component of the study included 359 individuals aged ≥60 years. ELC was present in 175 subjects. On MRI, 107 participants did not have WMH, 174 had mild, 56 had moderate, and 22 had severe WMH. A multivariate ordinal logistic regression model did not show a significant association between the main variables investigated (OR: 0.72; 95% C.I.: 0.48 – 1.06). The longitudinal component included 252 individuals, 126 of whom had ELC and 103 had WMH progression. A Poisson regression model showed no association between ELC and WMH progression (IRR: 1.02; 95% C.I.: 0.69 – 1.51).
Conclusions: ELC is not related to WMH severity and progression in the study population.
Leer artículo completo
Evaluación de la calidad de las guías de práctica clínica sobre enfermedad vascular cerebral aguda mediante la herramienta AGREE II. Quality assessment of clinical practice guidelines on stroke using the AGREE II tool
SummaryObjetive: Evaluate the quality assessment of the treatment guidelines for stroke between 2010 and 2021.
Methods: Evaluation by AGREE II instrument. Intraclass correlation was performed for two observers, and it was analyzed the consensus on blood pressure goals and the use of prehospital scales.
Results: 21 clinical practice guidelines were included. The consensus between observers was 0.88 (95% CI: 0.69-0.95). The highest score was for clarity of presentation, while the lowest was for applicability. Nine guidelines (42.9%) were “recommended,” seven were “not recommended” (33.3%) and five were “recommended, but with modifications.” There is consensus on the blood pressure goals in the initial phase. The Fast scale was the most recommended.
Conclusions: Less than half of the guidelines analyzed were recommended for clinical use. Since 2016, the guidelines have shown substantial improvements in their quality. Implementing and actively utilizing the guidelines demands strengthening the applicability and editorial independence.
Leer artículo completo
Escala de Conocimiento de la Enfermedad de Alzheimer: Adaptación y Análisis de las Propiedades Psicométricas en Estudiantes Universitarios Ecuatorianos. Alzheimer’s Disease Knowledge Scale: Adaptation and Analysis of Psychometric Properties in Ecuadorian University Students
SummaryThe aim of this study was to develop a linguistic adaptation of the Alzheimer’s Disease Knowledge Scale (ADKS), and to provide evidence on the reliability and validity of the adapted test. The ADKS is a self-administered instrument that examines knowledge about risk factors, assessment and diagnosis, symptoms, course, impact on life, care and treatment and management of Alzheimer’s disease (AD).
Methods: An instrumental study was implemented. The ADKS items were adapted to the Ecuadorian use of the Spanish language through an iterative process of translation by experts. Next, a sample of 523 university students completed the adapted scale together with a set of other instruments to analyze the fiability and criterion validity of the scale.
Results: ADKS Ecuador showed good internal consistency (Cronbach’s α=.78), adequate test-retest reliability, p > .05, and convergent and discriminatory evidence of validity when related to other variables.
Conclusion: ADKS Ecuador is an adequate instrument to assess general knowledge about AD in young highlgy educated Ecuadorian population with low dom ain knowledge.
Leer artículo completo
Prevalencia de deterioro cognitivo leve en peruanos adultos mayores y de mediana edad. Cognitive impairment prevalence in peruvian middle-age and elderly adults
SummaryAppraisals of dementias worldwide envisage an unfavorable scenario, especially in developing countries. Since factors such as education, socioeconomic status and healthiness play an important role in the development of Alzheimer’s disease and other dementias. It is known that pathophysiological features begin up to 20 years before an Alzheimer’s diagnosis and that the disease transits through three stages that include normal aging, mild cognitive impairment, and Alzheimer’s disease. The objective of this study was to determine the prevalence of cognitive impairment in a sample of middle-aged and older adults in southern Peru. A discriminant cognitive evaluation is performed for the absence or presence of cognitive alteration, focused especially on memory, language, visuoperception/visuoconstruction and other cognitive domains. Mini-Mental State Examination, Clock´s Test, and Verbal Fluency test were used, obtaining prevalence data for cognitive impairment with adjusted cut-off points according to age ranges (50-98 years) sex and education. Parametric and non-parametric statistics, logistic regression, Pearson correlation and ANCOVA were performed. The most suitable cut points for our population were selected through the ROC curves and the Youden index. The percentage of global mild cognitive deterioration was 58.80%. It is necessary to generate more effective mental health policies, especially referring to the middle-aged and elderly population, that address the early detection of MCI and Alzheimer’s disease.
Leer artículo completo
Impacto de los trastornos motores del habla y deglución sobre la calidad de vida de personas con enfermedad de Parkinson: una revisión sistemática de la literatura. Impact of motor speech and swallowing disorders in quality of life of people with Parkinson’s disease: a systematic review of the literature
SummaryParkinson’s disease (PD) is the second most common neurodegenerative disorder after Alzheimer’s-type dementia. It is known that these types of diseases cause a significant decline in the quality of life of the people who suffer from them and in their next of kin. Understanding the physical and psychosocial effects of neurodegenerative diseases contributes to clinical decisionmaking. It is for the above mentioned that the present study aims to examine the current evidence regarding the direct impact that phonoaaudiological disorders of motor origin generate on the quality of life in people with PD. A systematic review of the literature was carried out. The articles were searched in the following databases: PUBMED, SCIELO and WOS, during the months of June and July of the year 2020, constituting a sample of 12 works, with a maximum age of 10 years. The analysed publications mainly describe the aspects of quality of life that are affected in people with PD, who suffer dysphagia or dysarthria, all this through the application of different questionnaires which evaluate different aspects of this concept. The results of the review show the importance of considering within the intervention process the component of quality of life in people with E.P, since the scores obtained according to the instruments applied indicate a decrease of this component and even more with the progress of the disease, which translates into worse quality of life related to food and speech.
Leer artículo completo
Perfil de efectividad y seguridad de preparaciones orales de cannabis para el tratamiento de epilepsias refractarias en la población infantojuvenil. Una revisión de alcance. Effectiveness and safety profile of oral cannabis preparations for the treatment of refractory epilepsies in infant-young population: A Scoping Review
SummaryIntroduction: Refractory epilepsies (RE) are a common neurological condition expressed in childhood and adulthood, highlighting the current use of cannabis as an alternative treatment. Oral Cannabis Preparations (OCP) have demonstrated effectiveness in the adult population; however, knowledge is limited in the infant-young population.
Aim: To synthesize the available evidence on the efficacy and safety of OCP for the treatment of refractory epilepsies in the infant-young population.
Methods: The present study followed the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews) guidelines and included studies from January 2013 until December 2020 from electronic databases, including SciELO, ScienceDirect, PubMed, and Web of Science.
Results: 7 articles were included in this scoping review for critical analysis. The results indicate that pharmaceutical and artisanal origin OCP has 41.3% effectiveness in reducing seizures and low safety after administration (≤ 27.4%). Likewise, after administration, the most frequent adverse symptoms were somnolence/fatigue, weight loss/decreased appetite, and irritability/aggressiveness.
Conclusion: The low levels of effectiveness and safety of OCP suggest that they should be administered with caution and as a complementary treatment and not as the first choice for managing RE in the infant-young population.
Leer artículo completo
Hemorragia en área dependiente de circulación cerebral posterior por síndrome de hiperperfusión tras stenting en arteria carótida interna. Hemorrhage on a dependent area of posterior cerebral circulation due to hyperperfusion syndrome after stenting in internal carotid artery
SummaryCerebral hyperperfusion syndrome (CHS) after stent placement has a low incidence, between 0.37- 1.9% (1,2). We present a case of CHS due to recanalization in right internal carotid artery (ICA) which, contrary to expectations, produces a hematoma on a dependent area of the posterior cerebral circulation. Through the clinical case, we proceed to delve into the CHS and the characteristics that give the patient a higher risk. In addition, we expose the potential usefulness of the neurosonological study of inter-individual variability for better perioperative management. In this way, we can ensure a good therapeutic approach that minimizes morbidity and mortality as much as possible.
Leer artículo completo
Neuropatía craneal múltiple: Posible asociación a infección por HTLV 1. Multiple cranial neuropathy: Possible association with HTLV 1 infection
SummaryHuman lymphotropic virus type 1 (HTLV 1) is an oncoretrovirus that chronically and persistently infects T lymphocytes; which can cause serious neoplastic or inflammatory diseases, however, most are asymptomatic and only a small number of patients develop the disease. Although this virus particularly affects the hematological system in the form of T-cell leukemia or lymphoma, the nervous system is also an important target, both the central and peripheral components. In recent years, different associations have been found between this viral infection and multiple neuroinflammatory pathologies such as encephalitis, motor neuron diseases, polyneuropathies, cranial neuropathies and even myopathies, enriching the syndromic spectrum of this entity. On this occasion, the clinical particularities of a rare and possible association between HTLV 1 and multiple cranial neuropathy expressed in a patient managed in a tertiary care hospital in Cali, Colom bia will be described.
Leer artículo completo
Síndrome de cabeza caída en Miastenia gravis tras una infección por SARS-CoV2. Dropped head syndrome in Myasthenia gravis after a SARS‐CoV2 infection
SummaryObjective: To report a case with an unusual presentation of myasthenia gravis after a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and literature review.
Method: We report a case of a patient with head drop and a postsynaptic myasthenic syndrome after a SARS-CoV-2 infection and a retrospective review of the literature of all the reported cases of myasthenia gravis de novo associated with SARS-CoV2 infection from march-2020 to september-2022. Written informed consent was obtained from the patient for publication of this case report and accompanying images or videos.
Conclusion: Myasthenia gravis could also be the result of an autoimmune re action triggered by SARS-CoV-2 infection.
Leer artículo completo
Rehabilitación neuropsicológica de la memoria de trabajo sobre la conducta ejecutiva y el rendimiento académico en un niño con trastorno específico del aprendizaje. Neuropsychological rehabilitation of working memory on executive behavior and academic performance in a child with specific learning disorder
SummaryIntroduction: Learning disorders are a clinical condition that manifests itself at school age, affecting the cognitive, social and emotional functioning of the individuals who suffer from it. There are studies that show a positive effect of interventions on executive functioning, impacting the executive behaviors and ac ademic performance of children.
Objective: To assess the effect of a neuropsychological rehabilitation program for working memory on executive behavior and academic performance in a child with specific learning disor der.
Clinical case: An 11-year-old boy, diagnosed with a specific learning disorder according to the DSM-5, a working memory rehabilitation program was designed and applied and its impact on executive behaviors and academic performance was measured.
Results: The measurements of the treatment phase show a downward trend reflecting a positive impact. For the global index of executive function, the percentage of data that exceeds the median (PEM= 100%) indicates a very effective treatment and the non-overlapping of all pairs (NAP=89%) indicates a medium effect of the intervention.
Discussion: The results suggest a positive impact at the level of cognitive, behavioral and emotional functioning of the patient, reflected in executive behavior and academic performance.
Leer artículo completo
From hypokinesia to hyperkinesia: An 86-year-old-woman with abnormal movements. De hipocinesia a hipercinesia: Mujer de 86 años con movimientos anormales
SummaryAn 86-year-old woman presented with an acute onset of confusion, garbled speech, and decreased left arm movement. On exam, she had a forced right gaze, left homonymous hemianopsia, left hemiparesis, and left face and arm hypoesthesia. Forty-eight hours after successful revascularization therapies, the patient started complaining of abnormal involuntary movements. This manuscript discusses the phenomenology of these involuntary movements, their neuroanatomical correlates, management, and evolution. Neurologists should be mindful of post-stroke movement disorders, their latency period after stroke, and the functional-anatomic networks involved.
Leer artículo completo
Rol de los canales de sodio voltaje dependientes en la fisiopatología de la neuralgia del trigémino. Role of voltage-dependent sodium channels in the pathophysiology of trigeminal neuralgia
SummaryTrigeminal neuralgia is a severe chronic disorder that causes paroxysmal pain and dramatically decreases the quality of life of its patients. Although the pathophysiology of this disease has been extensively studied, the underlying molecular processes are still unclear, especially the role of voltage-dependent sodium channels in the triggering of painful crises. The main objective of this review is to summarize and update the important role of voltage-dependent sodium channels in the pathophysiology of trigeminal neuralgia, emphasizing the structural, functional and genetic alterations of these channels. It is concluded that trigeminal neuralgia is related to both congenital and acquired alterations in the e xpression of various voltage-dependent sodium channel isoforms.
Leer artículo completo
Genotipo polimórfico del gen MAOA y comportamiento antisocial en adolescentes y adultos varones. Polymorphic genotype of the MAOA gene and antisocial behavior in adolescent and adult males
SummaryStudies have shown the relationship between polymorphisms of the MAOA gene and the development of antisocial behavior, as men with low activity polymorphisms (MAOA-L) are more susceptible to develop violent behaviors than men with high activity polymorphisms (MAOA-H). The objective of the present work was to analyze the available scientific literature on the relationship of the polymorphic genotype of MAOA and the development of antisocial behavior in men, considering the environment as a genotypic modulator. A bibliographic review was carried out. Articles were selected whose sample consisted of male adolescents and adults with polymorphisms of the MAOA gene. Studies in women, reviews, unpublished data, and animal models were omitted. Twelve articles were analyzed: 10 studies (83.4%) concluded that the MAOA-L genotype plus childhood adversities, psychosocial factors, or alcoholism, had a higher risk of developing antisocial behaviors, 1 study (8.3%) concluded that the MAOA- genotype- H, associated with excessive alcohol consumption and abuse during childhood, had a higher risk of committing crimes and 1 study (8.3%) suggested the non-existent relationship between the MAOA-SNPs genotype and violence. We concluded that men with MAOA-L associated with environmental factors are more susceptible to develop antisocial behavior than those with the MAOA-H genotype.
Leer artículo completo
Relación entre el desarrollo psicomotor y funciones ejecutivas en la primera infancia de niños/as de 3 a 5 años. Relationship between psychomotor development and executive functions in early childhood of children from 3 to 5 years old
SummaryPsychomotor development is understood as the maturation of the central nervous system, which progresses as the child goes through stages in a linear and systematized manner. In relation to executive functions, these are known as a series of mental processes that allow managing and coordinating thoughts, emotional responses, and behavior. The main objective of the research was to analyze the relationship between psychomotor development and executive functions in children between 3 and 5 years old. For this, a bi bliographical systematic review study was carried out on psychomotor development and executive functions in children aged 3 to 5 years in the last 10 years. Likewise, the Scielo database was considered, and the observation technique was used to extract the information and bibliographic records were manipulated as a data collection instrument. The findings found that psychomotor development and executive functions are related, given that they have a predictive value in certain child development deficits. It can be concluded that language, social development, and motor skills are associated with cognitive processes, such as inhibition and working memory. In this sense, it is considered relevant that, in this age range, given the early psychomotor development and executive functions, nursery educators must be trained in this subject so that they can generate early intervention plans adapted for the promotion and prevention of certain deficits in early childhood development.
Leer artículo completo
Perspectiva histórica y actualidad de los síndromes antigangliósidos. Historical perspective and current scenarios of the antiganglioside syndrome
SummaryThe antiganglioside syndromes constitute a large clinical spectrum. Its knowlegde has evolved from the classical pure clinical descriptions to a wide development of the immunopathology underlying these processes and its possibilities of treatment.
In this work we realize a bibliographical review analyzing its evolution from a historical perspective to date at four levels: clinical, topographic, immunologic, and therapeutic. We analyze critically well-known topographical and immunologic notions that are scarcely integrated in daily clinical practice. We debate about the need of establish a new nomenclature for these syndromes in two levels: clinical and immunologic. Finally, we review the current and under development therapeutic lines.
Leer artículo completo
Perfiles cognitivos-lingüísticos en personas mayores con Deterioro Cognitivo Leve, Demencia Vascular, Demencia con Cuerpos de Lewy y Enfermedad de Parkinson. Cognitive-linguistic profiles in older people with Mild Cognitive Impairment, Vascular Dementia, Dementia with Lewy Bodies and Parkinson’s Disease
SummaryIntroduction: There is a wide heterogeneity of neuropsychological symptoms reported in pathological ageing. Current research has focused on patients with Alzheimer’s disease and frontotemporal dementia. However, still no detailed knowledge of the cognitive-linguistic profiles in patients whit Mild Cognitive Impairment (MCI) and other forms of dementia.
Objective: To characterize cognitive and linguistic profiles in older people with MCI, vascular dementia, Lewy body dementia, and Parkinson’s disease.
Methods: The present study followed the PRISMA guidelines and included studies from the PubMed, Scopus, and Web of Science databases, published between 2000 and 2020.
Results: 49 articles were included in this literature review for critical analysis. Older people with MCI, vascular dementia, Lewy body dementia, and Parkinson’s disease shows a significant decline in the following cognitive domains: memory, executive function, attention, and visuospatial/visuoconstructive skills. However, linguistic symptoms are also reported, especially the deficit in verbal fluency (semantic and phonological) and syntactic-grammatical and discursive skills.
Conclusion: This literature review characterized cognitive-linguistic profiles in older people with MCI, vascular dementia, Lewy body dementia, and Parkinson’s disease. These profiles could be helpful in clinical practice to improve early neuropsychological assessment processes and even determin e differential diagnoses between these clinical conditions.
Leer artículo completo
Paraproteinemic Neuropathies: A Review for Neurologists Neuropatías. Paraproteinémicas: Revisión de tema para Neurólogos
SummaryAs part of the workup of polyneuropathy, neurologists often encounter patients with paraproteinemias, also called monoclonal gammopathies. Given the relatively rising prevalence of both polyneuropathy and paraproteinemias in our aging population, this coexistence is frequently due to chance. Still, certain types of paraproteinemias have a well-defined causal role in the development of polyneuropathy, and therefore has implications in their subsequent work-up and management. Once a monoclonal gammopathy has been deemed as “benign” or of undetermined significance, looking at the heavy chain subtype is paramount in deciding whether it is related to a polyneuropathy. Conversely, polyneuropathies associated with monoclonal gammopathies tend to have a distinct clinical, serological, and/or electrodiagnostic phenotype that helps in establishing an association. Recognizing this association will determine approp riate workup and management.
Leer artículo completo
Embolismo gaseoso cerebral: a propósito de un caso de ictus masivo. Cerebral air embolism: about a case of massive stroke
SummaryIntroduction: Cerebral air embolism is a rare but potentially fatal entity, that occurs due to the entry of air into the cerebral blood circulation and is caused by multiple causes, including t hose associated with medical procedures.
Clinical case: We present the case of an 81-year-old male patient who, after removal of the high-flow hemodialysis catheter, begins with a deterioration of the level of consciousness, which worsens progressively. Multiple hypodense lesions, compatible with gas embolism, are evidenced in the cerebral tomography. Due to his slow evolution, he was transferred to the intensive care unit and died a few hours later.
Conclusion: It is essential to know the preventive measures to avoid this complication and the general and specific measures to adopt when it occurs.
Leer artículo completo
Psicosis orgánica, tipo trastorno esquizofreniforme, posterior a hemorragia subaracnoidea. Organic psychosis, schizophreniform disorder type, after subarachnoid hemorrhage
SummaryOrganic psychosis refers to a group of diseases currently classified as “mental disorders due to a medical illness”, unlike the absence of specific organic causality that exists in primary disorders. These are secondary to long-term processes , which is necessary to re-evaluate frequently due to the association between age-related deterioration, comorbidity and the evolution of psychosis itself. We present the case of a patient with subarachnoid hemorrhage secondary to a ruptured arteriovenous malformation, who suffered from a slight change in behavior and decreased cognitive functions with subsequent evolution to dissociative symptoms, episodes of hypersomnia and disconnection from the environment, through assessment joint of specialties was reached the diagnosis of organic psychosis type schizophreniform disorder.
Leer artículo completo
Infarto cerebeloso bilateral simultáneo en un paciente con fibrilación auricular paroxística no valvular: una presentación atípica. Simultaneous bilateral cerebellar infarction in a patient with paroxysmal atrial fibrillation: an atypical presentation
SummaryIntroduction: Cerebellar infarcts usually occur in the territory of the posterior inferior cerebellar artery (PICA) and tend to be unilateral. Simultaneous bilateral involvement is extremely rare.
Case report: We present the case of a 67-year-old male who developed an acute cerebellar syndrome secondary to acute infarction in the territory of both PICA confirmed by nuclear magnetic resonance imaging. Non-valvular paroxysmal atrial fibrillation was the most plausible etiology after digital cerebral angiography ruled out vascular abnormalities.
Conclusion: This case shows that bilateral infarction in the territory of both PICA can occur in the context of cardiac embolism, even in the absence of an anomalous common PICA.
Leer artículo completo
Infarto cerebral en mujeres. Stroke in women
SummaryLeer artículo completo
Disfunción neurológica y exposición a agrotóxicos. Neurological dysfunction and exposure to agrotoxics
SummaryLeer artículo completo
Plantas medicinales: Comprendiendo sus beneficios para la salud y advirtiendo sobre sus efectos psicoactivos y neurotóxicos. Medicinal plants: Understanding their health benefits and warning about their psychoactive and neurotoxic effects
SummaryLeer artículo completo
Beneficios de la musicoterapia sobre el lenguaje. Benefits of music therapy on language
SummaryLeer artículo completo
Embarazo y esclerosis múltiple: ¿Existe una relación positiva entre ambas entidades? Pregnancy and multiple sclerosis: Is there a positive relationship between the two?
SummaryLeer artículo completo
Factores asociados al tiempo libre de discapacidad en pacientes con Esclerosis Múltiple de un instituto de neurología en Medellín, Colombia. Factors associated with disability-free time in patients with Multiple Sclerosis of a neurology institution in Medellin, Colombia
SummaryIntroduction: Multiple Sclerosis is the leading neurological cause of disability in young adults. The objective of this study was to describe the time free from disability since diagnosis and to analyze associated factors.
Method: Retrospective follow-up study of a cohort based on records of patients who consulted the Neurological Institute of Colombia between 2013 and 2021. Progression to disability was defined as the time to obtain a value greater than 3.5 on the EDSS scale. Parametric survival model for interval censored data with Weibull distribution was used to estimate survival function and Hazard Ratios.
Results: 216 patients were analyzed. The median disability-free time was 12 years (95% CI 7.56-17.66). Cerebellar complications (aHR = 8.18; 95% CI 4.09-16.35), vision (aHR = 2.25; 95% CI 1.25-4.05) and age at diagnosis over 40 (aHR = 1 .28; 95% CI 0.68-2.4) were associated with shorter time to progression, other initial symptoms (aHR = 0.35; 95% CI 0.18-0.68), stem lesions (aHR = 0.6; 95% CI 0.33-1.1), MSRR (aHR = 0.17; 95% CI 0.08-0.33) and women were associated with a longer time to progression.
Conclusion: Clinical and imaging factors allow identifying patients at high risk of rapid progression to disability.
Leer artículo completo
Correlación entre variables clínicas sugestivas de hipertensión intracraneal y alteraciones en la neuroimagen en trauma craneoencefálico. Correlation between clinical variables suggestive of intracranial hypertension and alterations in neuroimaging in traumatic brain injury
SummaryMethods: Retrospective observational cohort study where patients admitted for TBI to the ICU area of the HLV were included.
Results: We included a total of 297 subjects. The most common neuroimaging lesion was multiple lesions (35.4%). We found that there is a significant correlation between the presence of lesion in neuroimaging and the presence of fixed pupils at admission (p = <0.001), score ≤ 8 on the Glasgow scale (p = <0.001) and need for orotracheal intubation (p = <0.001). Similarly, the same 3 variables were significant when related to the score ≥ III on the Marshall scale. In the logistic regression model, pupil fixation was the only one that was shown to increase the risk of a score ≥ III on the Marshall scale (OR: 3.50, 95% CI 1.53-7.99).
Conclusion: The clinical variables: pupil fixation, need for endotracheal intubation and Glasgow ≤ 8 are related to the development and severity of lesion on neuroimaging in patients with TBI.
Leer artículo completo
Entrenamiento sensoriomotor en casa en personas mayores con Enfermedad Parkinson durante el periodo de confinamiento por COVID-19: Estudio piloto. Sensorimotor training at home in elderly people with Parkinson’s Disease during the period of confinement due to COVID-19: A pilot study
SummaryThe pandemic caused those therapeutic activities associated with people with Parkinson’s disease to be suspended (PD) with the aim of preventing COVID-19 infections by increasing motor and non-motor symptoms, due to social isolation and stress. Therefore, there was a rise of care based on telemedicine to continue the treatment in the context of a health emergency, promoting training at home. The objective of this experimental research was to document the effects of a sensorimotor training program (NM-FITT®) in people with PD through weekly telematic follow-up during the COVID-19 pandemic. A quasi-experimental study was carried out with pre, inter and post test evaluations that characterized the physical, functional condition and quality of life, in an intervention group (n=5) and a control group (n=5) of elderly people (69.5 ±4.5 years) with PD in Hoehn & Yahr stages 1 to 3, for 18 weeks, through an exercise manual, video calls and telephone follow-up. Favorable and significant effects were demonstrated on all the parameters studied after the application of the intervention in detriment of the health condition of the persons who did not participate in the home training program.
