The high association of depression and dementia in the elderly has motivated to investigate the type of relationship that exists between them. The objective of this narrative review was to describe the relationship between depression and dementia, for which the Medline, Science Direct, Dialnet, Redalyc databases were reviewed between 2000 and 2021, with the verbal descriptors “dementia” AND “depression” AND “relationship” AND “older adult” OUT “caregiver depression” to locate the candidate documents and then select the final sample made up of 60 published articles, which were reviewed by three judges for selection. Seven explanations of the relationship between dementia and depression were identified in which depression is considered a risk factor for dementia, a prodrome, a consequence, among others. Likewise, there was evidence that, although all the hypotheses have scientific support, there are also indications of their refutability. The types of relationship with the greatest scientific support were “depression as a risk factor” and “as a prodrome of dementia”, although the limitations in the studies prevent clarifying the relationship between these entities. Longitudinal studies that review the history of depression are suggested as a useful methodology to determine the relationship between them.
risk factor
Relación entre la depresión y la demencia. Relationship between depression and dementia
Epilepsia Como Factor Pronóstico de Refractariedad y Funcionalidad en Estado Epiléptico en Pacientes Mexicanos. Epilepsy As Prognostic Factor Of Refractoriness And Functionality In Status Epilepticus In Mexican Patients.
Introduction: Status epilepticus is a medical condition which could lead to a great disability and be mortal. Background of epilepsy could prevent a progression to a refractory status epilepticus and predict a good functional prognosis. Nevertheless, in Mexican population there are no studies about that.
Materials and methods: An observational, analytic, retrospective, cohort study was performed with patients with status epilepticus in Specialities Hospital of “Siglo XXI” National Medical Center, in Mexico. It was evaluated the probability of presenting refractory status epilepticus and a good functional outcome in patients with a background of epilepsy, performing Pearson Chi-square.
Results: 40 patients with status epilepticus were included, 32 with refractory status epilepticus and 14 with a background of epilepsy. The probability of presenting a refractory status epilepticus with a background of epilepsy was OR 1.29 (p 0.53), and for a good functional outcome was OR 3.63 (p 0.10).
Conclusions: Background of epilepsy is not a protective factor for preventing the progression to a refractory status epilepticus, neither a factor for predicting a good functional outcome in our study with Mexican population. Nevertheless, further studies with a bigger sample are needed in order to prove these results.
