Publicación Oficial de la Sociedad Ecuatoriana de Neurología, de la Liga Ecuatoriana Contra la Epilepsia y de la Sociedad Iberoamericana de Enfermedad Cerebrovascular

tomografía computada

 

Tiempo en Horas Desde el Inicio del Deterioro Neurológico en Pacientes con un Evento Cerebrovascular Isquémico hasta su Llegada a la Sala de Emergencia. Estudio Observacional Time In Hours From The Beginning Of Neurological Deterioration In Patients With Ischemic Stroke To Arrival At The Emergency Room. An Observational Study

Patients who present neurological symptoms compatible with an ischemic cerebrovascular event benefit from the use of alteplase (intravenous thrombolysis) as long as it is administered within 4.5 hours after the onset of symptoms.

Objective: Establish the time in hours that it takes our patients to arrive at the Emergency Department of the General Hospital Del Norte in Guayaquil Los Ceibos, Ecuador.

Methods: It is an observational, descriptive cross-sectional study that included 157 patients with a diagnosis of acute ischemic cerebrovascular event by computed tomography and/or magnetic resonance imaging and who attended the emergency room of our hospital between January and June, 2022 and from February to April 2023. Other variables such as percentage of thrombolyzed patients, sex, average age, age groups, blood pressure at admission and localization of the cerebral infarct were also studied.

Results: The average time in arrival hours was 34.7 hours, of which 18 (11.5 %) arrived up to 3.0 hours, 14 (8.9%) between > 3.0 to 4.5 hours and 125 subjects (79.6%) arrived after 4.5 hours from the onset of symptoms. Only 3.2 % of patients were thrombolyzed. Men were affected in 64.3% and women in 35.7%. The average age was 69 years old; by age groups, the vast majority ocurres after age 50 and only 8.3 % before that age. 72.6% were hypertensive and of these, 62.3% were male and 37.7% were female; by age groups, we see that 81.6% of hypertensive patients are between 60 and 89 years old. Regarding the location of the infarction, of all patients, the anterior territory is affected in 64.5% of cases and the posterior territory in 35.5%. Conclusions: Our patients arrive very late to the emergency room, well beyond the 4.5 hours that is the time during which they would benefit from thrombolytic treatment, the highest percentage of events ocurres after the age of 50, the majority are men, most arrive with hypertension and the anterior brain territory is more affected than the posterior.

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Sub-estudio de Neuroimagen del Proyecto Atahualpa. Neuroimaging Substudy Of The Atahualpa Project

The Atahualpa Project includes a Neuroimaging sub-study, which consists in the practice of MRIs and MRAs to all participants aged ≥60 years, as well as those presenting with specific neurological complains. Likewise, all participants aged ≥20 years have been invited for the practice of a head CT. MRIs and MRAs have been performed with the use of a Philips Intera 1.5T MRI machine, and TCs with the use of a Philips Brilliance 64 CT scanner, following established protocols. All exams have been independently reviewed by a neurologist and a neuroradiologist, with adequate kappa coefficients for inter-rater agreement. MRIs studies have been focused on the evaluation of global cortical atrophy, posterior parietal atrophy, bicaudate index, Evans index, hippocampal atrophy, signatures of cerebral small vessel disease, and lesions consistent with ischemic or hemorrhagic strokes. By the use of MRI, we have assessed the prevalence of intracranial artery stenosis, intracranial dolichoectasia and variations in the configuration of the circle of Willis. Using CT, we have focused on the diagnosis of neurocysticercosis, pineal gland calcifications, as well as in variations and characteristics of skull bones, cerebellar atrophy, and severity of carotid siphon calcifications. In the present study, we focused on the description of basic protocols used for assessment of previously mentioned lesions of interest.

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