Publicación Oficial de la Sociedad Ecuatoriana de Neurología, de la Liga Ecuatoriana Contra la Epilepsia y de la Sociedad Iberoamericana de Enfermedad Cerebrovascular

Linfoma

 

Linfoma Primario de Sistema Nervioso Central: Un Desafío Diagnóstico. Primary Lymphoma of the Central Nervous System: A diagnostic challenge.

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Enfermedad Celiaca. Alteraciones Neurológicas y Enteropatía Asociada a Linfoma de Células T.

In celiac disease, gluten ingestion results in intestinal mucosal swelling, cryptic hyperplasia, and villi atrophy in genetically predisposed individuals. We report an unusual case of celiac disease, neurological complications and enteropathy associated T cell lymphoma in the same patient.

Case report: A 49 year-old woman with celiac disease who failed to respond to a strict free-gluten diet. She developed intestinal perforation, T cell lymphoma associated to enteropathy and neurological features.

Conclusion: An uncommon case of celiac disease with associated neurological manifestations and malignancy. In a single patient, this uncommon association has not been reported. It is still to be determined, whether genetic and/or immunological factors are responsible for the development of this features.

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Trombosis Venosa Cerebral en una paciente con Linfoma no Hodgkin en remisión.

Introduction: Cerebral venous thrombosis is an unusual complication, scarcely reported in patients with non-Hodgkin lymphoma with indolent and not too aggressive type.

Case report: We describe the clinical picture of a woman with low degree non-Hodgkin lymphoma with an evolution of one year remission post treatment, who developed a sinus rectus thrombosis without relationship with intracranial extension nor treatment induced hypercoagulability state. The first manifestation was isolated migraine.

Conclusion: In patients with non-Hodgkin lymphoma and isolated migraine is important to perform neuroimaging studies in order to exclude a cerebral venous thrombosis.

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