The discovery of aquaporins, which constitute a family of integral membrane proteins, has meant a change with respect to the understanding of water transport in biological membranes. The most important is aquaporin 4 (AQP4) which we will focus on below, although there are two other aquaporins, 1 and 9. These aquaporins are of great importance in the physiology of cell volume control and osmotic control mechanisms of the cells. Also in the control of the flow of glycerol and other solutes. In addition, alterations in its functioning have been related to various diseases of the central nervous system such as neuromyelitis optics, cerebral edema, idiopathic intracranial hypertension or chronic hydrocephalus of the adult among others. A review is made on this topic.
Intracranial hypertension
Las Aquaporinas y el Sistema Nervioso Central. Aquaporins and Central Nervous System.
Palabras clave: Aquaporin 1,
Aquaporin 4,
Aquaporins,
central nervous system,
Cerebrospinal fluid,
Intracranial hypertension,
