We report the case of a 63-year-old man who initially presented with hearing loss and optic neuritis. He subsequently developed vertigo, and multiple multitopographic cerebral infarctions were documented, with negative vascular risk factor evaluation. Panangiography revealed findings suggestive of central nervous system vasculitis, and the initial lumbar puncture showed no evidence of infection; therefore, an immune-mediated vasculitis was considered. Following further neurological deterioration, central nervous system infection due to Cryptococcus neoformans was confirmed. This case highlights the diagnostic challenge and the limitations of initial microbiological testing in central nervous system cryptococcosis.
Prozone phenomenon
Criptococosis con Vasculitis del Sistema Nervioso Central Mediada Inmunológicamente: Un Reto Diagnóstico. Cryptococcosis with Immune-Mediated Central Nervous System Vasculitis: A Diagnostic Challenge
Palabras clave: Criptococosis,
efecto prozona,
Síndrome de Cogan,
Vasculitis del sistema nervioso central,
