Since 1961, the overlap between myasthenia gravis (MG) and systemic lupus erythematosus (SLE) has been increasingly recognized, with MG patients facing up to 13 times the risk of developing SLE, especially after thymectomy, predominantly in young women. Thymic B cells may play a role in MG and SLE, as shown in animal models. MG often coexists with family histories of autoimmune diseases, sharing genetic risk factors with SLE, as supported by genome-wide studies. Patients with both conditions also experience higher rates of other autoimmune diseases, suggesting a potential for broader autoimmunity. Early-onset MuSK-MG strengthens this observed connection.
Publicación Oficial de la Sociedad Ecuatoriana de Neurología, de la Liga Ecuatoriana Contra la Epilepsia y de la Sociedad Iberoamericana de Enfermedad Cerebrovascular
