This study aims to analyze medication adherence, quality of life, and non-motor symptoms in Parkinson’s disease patients in Azogues, Biblián, and Déleg. A descriptive and correlational approach was used, collecting data on various variables such as Age, Age at Diagnosis, Mobility, Daily Activity, Emotional Well-Being, Stigma, Social Support, Cognitive Status, Communication, Physical Discomfort, Medication Adherence, and Non-Motor Symptoms. The normality of variable distributions was assessed, and Pearson correlations were applied to examine their relationships. The results showed significant correlations between Age and other variables, such as Mobility, Daily Activity, and Emotional Well-Being. The relationship between Mobility and Daily Activity was extremely strong, and non-motor symptoms notably impacted quality of life, particularly Cognitive Status and Communication. The Gaussian graphical model revealed direct interactions between the variables. In conclusion, the research highlights how mobility, emotional well-being, and social support influence the quality of life of Parkinson’s patients, while non-motor symptoms negatively affect their overall well-being, suggesting key areas for intervention and improvement in the treatment of these patients.
Medication adherence
Análisis de Redes de Adherencia al tratamiento farmacológico, Calidad de vida y síntomas no Motores en pacientes con Parkinson de Azogues, Biblián y Déleg. Network analysis of adherence to pharmacological treatment, quality of life and nonmotor symptoms in Parkinson’s patients from Azogues, Biblián and Déleg
Investigating Lack Of Adherence To Medications Used For Primary Or Secondary Stroke Prevention In Rural Ecuador: Rationale And Protocol Of A Population-Based Study Investigación de la Falta de Adherencia a Medicamentos Utilizados para la Prevención Primaria y Secundaria de Ictus en Zonas Rurales del Ecuador: Fundamentación y Protocolo de un Estudio Poblacional
Background: Stroke is an emerging public health crisis in Latin America, particularly in rural areas of low- and middle-income countries (LMIC), where limited healthcare access exacerbates disease burden. Medication adherence plays a fundamental role in stroke prevention, yet information on this topic remains insufficiently known due to issues related to socioeconomic, educational, and infrastructural barriers.
Aims: This study introduces a protocol designed to assess adherence to primary and secondary stroke prevention medications in rural Ecuador. By identifying behavioral patterns and underlying barriers, this research aims to provide evidence-based recommendations for improving adherence and informing public health interventions.
Methods: The study will be conducted in Atahualpa, Ecuador, using a population-based design with an initial cross-sectional assessment followed by a 10-year longitudinal follow-up. Medication adherence will be evaluated through validated questionnaires, clinical examinations, and annual updates on vascular risk factors and social determinants of health. Statistical analyses will assess the relationship between adherence levels, demographic variables, and cerebrovascular outcomes.
Comment: This research provides essential insights into adherence behaviors in underserved populations, offering a foundation for targeted interventions. Findings will support healthcare accessibility, strengthen patient education, and improve adherence strategies to reduce stroke incidence and improve health outcomes in rural LMIC settings.



