Publicación Oficial de la Sociedad Ecuatoriana de Neurología, de la Liga Ecuatoriana Contra la Epilepsia y de la Sociedad Iberoamericana de Enfermedad Cerebrovascular

Aseptic meningitis

 

Enfermedad de Vogt-Koyanagi-Harada, revisión de literatura: Una entidad infrecuente con tratamiento efectivo. Literature review on Vogt-Koyanagi-Harada disease: An infrequent entity with effective treatment.

Introduction: Vogt-Koyanagi-Harada (VKH) disease is an uncommon systemic inflammatory disease of autoimmune etiology. It can present neurological, auditory, dermatological, and ophthalmological manifestations, it has a well-established natural clinical course with variations between different states, which constitutes a diagnostic challenge in clinical practice.

Development: A search of literature on Vogt-Koyanagi-Harada disease available until July 2023 in the databases PubMed and Scopus was carried out, including MeSH terms “Vogt-Koyanagi-Harada disease,” “Uveitis,” “Uveitis-Meningitis Syndrome,” “Aseptic meningitis.”

Conclusions: Vogt-Koyanagi-Harada disease is considered an infrequent and multifaceted condition, which constitutes a diagnostic challenge. There is evidence supporting a mechanism of autoimmunity mediated by T-lymphocytes against melanocyte antigens, the triggering factor is still uncertain. The diagnosis of this disease is clinical, associated with complementary imagenologic and laboratory exams, it is necessary to conform better diagnostic criteria to achieve an early diagnosis and treatment, oriented to obtain better clinic results for patients with this disease.

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