Objective: To demonstrate that the high leuko-glycemic index was a predictor of in-hospital mortality in patients with acute ischemic stroke of the Neurology Department at Belen of Trujillo Hospital in the period from January 2014 to December 2018.

Material and method: Observational, analytical, cohort and retrospective research, conducted at Belen of Trujillo Hospital, with a census sample of patients hospitalized in the Neurology department with diagnosis of acute ischemic stroke in the period from January 2014 to December 2018 , who met the selection criteria.

Results: 281 medical records were analyzed, where 18 were of deceased patients, of which 56% died with a leuko-glycemic index greater than 1600, the association being statistically significant (RRa: 6.33, CI: 95% [1.35 – 29.64]; p = 0.019). In addition, in the multivariate analysis, age greater than or equal to 80 years, admission moderate awareness disorder and in-hospital pneumonia were also relevant.

Conclusion: The high leuko-glycemic index was a predictor of in-hospital mortality in patients with acute ischemic stroke of the Neurology Department at Belen of Trujillo Hospital in the period from January 2014 to December 2018.