Publicación Oficial de la Sociedad Ecuatoriana de Neurología, de la Liga Ecuatoriana Contra la Epilepsia y de la Sociedad Iberoamericana de Enfermedad Cerebrovascular

tomography

 

Tiempo en Horas Desde el Inicio del Deterioro Neurológico en Pacientes con un Evento Cerebrovascular Isquémico hasta su Llegada a la Sala de Emergencia. Estudio Observacional Time In Hours From The Beginning Of Neurological Deterioration In Patients With Ischemic Stroke To Arrival At The Emergency Room. An Observational Study

Patients who present neurological symptoms compatible with an ischemic cerebrovascular event benefit from the use of alteplase (intravenous thrombolysis) as long as it is administered within 4.5 hours after the onset of symptoms.

Objective: Establish the time in hours that it takes our patients to arrive at the Emergency Department of the General Hospital Del Norte in Guayaquil Los Ceibos, Ecuador.

Methods: It is an observational, descriptive cross-sectional study that included 157 patients with a diagnosis of acute ischemic cerebrovascular event by computed tomography and/or magnetic resonance imaging and who attended the emergency room of our hospital between January and June, 2022 and from February to April 2023. Other variables such as percentage of thrombolyzed patients, sex, average age, age groups, blood pressure at admission and localization of the cerebral infarct were also studied.

Results: The average time in arrival hours was 34.7 hours, of which 18 (11.5 %) arrived up to 3.0 hours, 14 (8.9%) between > 3.0 to 4.5 hours and 125 subjects (79.6%) arrived after 4.5 hours from the onset of symptoms. Only 3.2 % of patients were thrombolyzed. Men were affected in 64.3% and women in 35.7%. The average age was 69 years old; by age groups, the vast majority ocurres after age 50 and only 8.3 % before that age. 72.6% were hypertensive and of these, 62.3% were male and 37.7% were female; by age groups, we see that 81.6% of hypertensive patients are between 60 and 89 years old. Regarding the location of the infarction, of all patients, the anterior territory is affected in 64.5% of cases and the posterior territory in 35.5%. Conclusions: Our patients arrive very late to the emergency room, well beyond the 4.5 hours that is the time during which they would benefit from thrombolytic treatment, the highest percentage of events ocurres after the age of 50, the majority are men, most arrive with hypertension and the anterior brain territory is more affected than the posterior.

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Correlación entre variables clínicas sugestivas de hipertensión intracraneal y alteraciones en la neuroimagen en trauma craneoencefálico. Correlation between clinical variables suggestive of intracranial hypertension and alterations in neuroimaging in traumatic brain injury

Methods: Retrospective observational cohort study where patients admitted for TBI to the ICU area of the HLV were included. 

Results: We included a total of 297 subjects. The most common neuroimaging lesion was multiple lesions (35.4%). We found that there is a significant correlation between the presence of lesion in neuroimaging and the presence of fixed pupils at admission (p = <0.001), score ≤ 8 on the Glasgow scale (p = <0.001) and need for orotracheal intubation (p = <0.001). Similarly, the same 3 variables were significant when related to the score ≥ III on the Marshall scale. In the logistic regression model, pupil fixation was the only one that was shown to increase the risk of a score ≥ III on the Marshall scale (OR: 3.50, 95% CI 1.53-7.99). 

Conclusion: The clinical variables: pupil fixation, need for endotracheal intubation and Glasgow ≤ 8 are related to the development and severity of lesion on neuroimaging in patients with TBI.

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