A 77-year-old man developed progressive slurry speech, action tremor in both upper limbs, generalized bradykinesia, and unsteady and shuffling gait several weeks after heavy binge-drinking followed by an unconsciousness state in which the patient did not respond to verbal commands or painful stimuli. MRI disclosed bilateral and symmetrical necrosis of globus pallidus as well as severe cortical and hippocampal atrophy. Damage of the globus pallidus was likely related to respiratory acidosis during the event. Pallidal Parkinsonism should be considered in the differential diagnosis of a progressive movement disorder after an acute toxic or hypoxic insult to the nervous system.
Pallidal Parkinsonism
Insuficiencia Hepática Crónica y Lesiones Palidales Bilaterales. Chronic Liver Failure And Bilateral Pallidal Lesions.
A 66-year-old woman with history of cirrhosis of unknown etiology was evaluated one month after transient loss of consciousness followed by dystonic posturing, abnormal speech and shuffling gate.
She had been complaining of chronic fatigue, anorexia and weight loos for the past six months, and referred two episodes of non-traumatic nose bleeding in the past two weeks.
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Palabras clave: cirrosis hepática,
degeneración hepatocerebral,
globo pálido,
Parkinsonismo pallidal,
