Publicación Oficial de la Sociedad Ecuatoriana de Neurología, de la Liga Ecuatoriana Contra la Epilepsia y de la Sociedad Iberoamericana de Enfermedad Cerebrovascular

Perú

 

Perfil Clínico y Demográfico de Pacientes con Enfermedad de Parkinson: Experiencia en un Centro de Referencia de Perú. Clinical And Demographic Characteristics Of Patients With Parkinson’s Disease: Experience At A Referral Center In Peru

Objective: To describe the demographic and clinical characteristics of patients with Parkinson’s disease treated at a national reference hospital in Peru.

Methods: We conducted a retrospective cross-sectional study that included 35 adult patients (18 years and older) with Parkinson’s disease treated at the Neurology outpatient service of the Edgardo Rebagliati Martins National Hospital during 2020. We recorded the clinical and demographic information of the medical records. clinics. We performed bivariate analysis to compare the covariates of interest with the presence of complications and the Hoehn and Yahr stage.

Results: The average time of illness was more than 5 years from diagnosis and most presented motor complications, the treatment they received was almost entirely levodopa and 37% received treatment with deep brain stimulation. In the bivariate analysis according to the Hoehn and Yahr stages with the variants age, clinical variant, time of illness and being subjected to Deep Brain Stimulation, no significant differences were found. In the bivariate analysis according to the presence of complications, statistical differences were found between complications and tertiles of age (p=0.008) and the median time of illness (p=0.010).

Conclusion: We report a prolonged disease time in the included patients, most of them presented motor complications, their main treatment was levodopa and a high percentage of deep brain stimulation. It is important to propose multicenter studies in reference centers for Parkinson’s management that allow us to have a better overview of the clinical and demographic situation of these patients in our population.

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Deterioro Cognitivo Leve: detección y costo de enfermedad en Perú. Mild Cognitive Impairment: screening and cost of illness in Peru.

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Niveles de Hemoglobina y Anemia en Niños: Implicancias Para el Desarrollo de Las Funciones Ejecutivas. Hemoglobin And Anemia Levels In Children: Implications For The Development Of Executive Functions

Introduction: Anemia is one of the most important health problems in the world. In developing countries; anemia coexists with malnutrition, lack of access to water, and sanitation. In Peru, more than 40% of children have anemia that affects their brain function and cognitive processes during their development, even to adult life.

Objective: This study sought (1) to know the levels of hemoglobin and the presence of anemia in children in rural and urban Arequipa, as well as other indicators of physical health, (2) compare the level of development of executive functions between both groups of children, and (3) analyzes of hemoglobin levels predict the cognitive profile.

Method: 49 subjects were evaluated (55% from rural area, 46% girls). Both groups begin regular basic education, different weight measurements were evaluated, including hemoglobin (HemoCuer®) and O2 saturation. The executive functions were assessed with the BANFE test.

Results: Disturbing levels of anemia have been found in the rural area of ​​Arequipa, as well as obesity in children in the urban area. Different processes of executive functions, especially from dorsolateral area have been reduced in rural children; despite having a similar educational and socioeconomic level. Finally, we found that hemoglobin levels explained the 27% of the variance; corresponding to the dorsolateral prefrontal score.

Conclusion: Anemia affects the development of executive functions in children, generating tombs consequences in their neurodevelopment.

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