Publicación Oficial de la Sociedad Ecuatoriana de Neurología, de la Liga Ecuatoriana Contra la Epilepsia y de la Sociedad Iberoamericana de Enfermedad Cerebrovascular

Atrofia Cerebral

 

Neuropsychological and brain atrophy pattern characterization in patients with stroke related to COVID infection: A systematic review. Caracterización neuropsicológica y del patrón de atrofia cerebral en pacientes con ictus relacionado a COVID: Una revisión sistemática.

Introduction: The high mortality rates in patients with COVID infection have been the main focus of interest in clinical and research practice. COVID infection has also been characterized by its respiratory consequences; however, several studies have reported neurological manifestations in this clinical population (e.g., stroke). From a neurological perspective, patients with stroke related to COVID infection remain challenging as well. No systematic reviews have yet focused on neuropsychological and neuroanatomical correlate profiles.

Aim: To characterize the neuropsychological profile and the pattern of brain areas affected in adult and older adults with stroke related to COVID infection.

Methods: The present study followed the PRISMA guidelines and included studies from the PubMed, Scopus, and Web of Sciences databases, published between January 2020 and September 2022.

Results: 7 articles were included in this systematic review for critical analysis. Ischemic stroke was the most reported in patients. Results suggest that the most reported neuropsychological declines are orientation, attention, memory, executive function, visuoconstructive skills, and language. The pattern of brain areas also considers right lesions in cortical and subcortical regions.

Conclusion: In patients with COVID-related strokes, lesions in the left hemisphere or bilateral are common, together with the expression of aphasia. Likewise, our findings reflect only ischemic patients’ cognitive and brain features. Therefore, results must be interpreted carefully.

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Palabras clave: Atrofia Cerebral, Correlato neuroanatómico, COVID-19, diagnóstico, evaluación neuropsicológica, Ictus,

Keywords: Atrophy pattern, COVID-19, diagnosis, Neuroanatomical Correlate, Neuropsychological assessment, stroke,

A strange case of Comorbidity in a 60-year-old Portuguese war veteran: War Post Traumatic Stress Disorder, Early Fronto- Temporal Cerebral Atrophy, and Strong Neuropsychological Symptomatology. A Neuropsychological Review.

The Post-Traumatic Stress Disorder is a psychiatric disorder that derives from traumatic events. Although the literature and clinical reports of PTSD is known along centuries, only in 1980 was recognized by the American Psychiatric Association as a diagnostic category of the Diagnostic and Statistical Manual – III. The present article reports the case study of a man with Post-Traumatic Stress Disorder, initial signs of fronto-temporal dementia and other neuropsychological and neuropsychiatric symptomatology. Decurrent of the neuropsychological evaluation was possible to detect a variety of alterations in the humour and personalistic sphere, as well as deficits in orientation, memory, attention, concentration and also in the functions regulated by pre-frontal cortex. This study suggests not only the importance of a deep neuropsychological evaluation, as the necessity to integrate the deficits showed by the patient with the evidence from literature.

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Palabras clave: Atrofia Cerebral, Comorbilidad, Demencia Fronto-Temporal, Perturbación de Estrés Pos-Traumático de Guerra, Valoración Neuropsicológica,

Keywords: Cerebral Atrophy, Comorbidity, Fronto-Temporal Dementia, Neuropsychological Evaluation, War Post-Traumatic Stress Disorder,
 
 
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