Parkinson’s Disease (PD) is a neurological illness due to degeneration of the dopaminergic neurons of the nigro-striatal pathway. Each of the five frontal-subcortical circuits contributes in a different way to PD’s symptoms. The clinical manifestations are variable; they include non cognitive deficits like: rigidity, tremor, bradykinesia, and other motor deficits like hypomimic (mask-like face), hypophonia, dysarthria, dystonia and abnormal postures among others. The emotional disorders in PD include depression and anxiety. The frontotemporal dementia in PD has been described. The neuropsychological examination of the PD patient is done considering whether the main symptoms are bradykinesia and rigidity, since these patients show more severe cognitive decline. We must examine the attention, which is between the normal limits in simple tasks, but it shows deficits in more complex tasks; memory and learning are disturbed, orientation is intact; in verbal functions we evaluate vocabulary, syntaxes and grammar which are relatively intact, although the sentence length tend to be reduced; the visuospatial disorders are frequent in PD; thinking and reasoning must also be examined, in both of them there is normal performance and they show a realistic appreciation of their condition and limitations; the executive functions are evaluated, there are consistent failures in tests that require concept formation and thinking flexibility. PD treatment can be medical using L-Dopa, or surgery through techniques by lesion or stimulation to different surgical targets like the internal globus pallidus, the subthalamic nucleus, or the ventral medial thalamic nucleus, unilateral or bilaterally. The PD repercussions in working memory (WM) will be studied related to executive functions, speech, cronometraje, saccades and attention.

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