There has always been an interest in understanding how the human brain functions in relation to behavior and cognition. An approach that seeks to solve this intrigue lies in the proposal of models of brain organization that try to explain how the work of the brain mass is. In this sense, this article proposes a theoretical review of the main models. Jackson proposes a theory where three levels of brain structure are considered: lower or medullary level, middle level, and higher level. McLean postulates the existence of three brains: reptile, paloemamiferous / limbic and neocortex. The Wernicke-Geswind model manifests the interaction of language structures in favor of brain function. Luria’s model of brain organization highlights the interactive role of three functional units: first, in charge of regulating tone and wakefulness; second, it receives, processes and stores the information; and the third, plans, monitors and verifies mental and behavioral activity. This review highlights the high complexity involved in the work of the human brain. This article closes highlighting the need to carry out research that can generate empirical evidence in favor of understanding the efficacy of each of the models described in this work.

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